My mom's mom's maiden name was Poff, and so I read stories about Poffs in the Roanoke and New River Valley areas (even though most of them, including lawyer Bill Poff and former Congressman and Virginia Supreme Court Justice Richard Poff, are not related to me in any way that I know about). Here is a story on the death of a man from Pilot, Virginia, named Poff who died of ALS.
I was out on the golf course at the Virginian yesterday, as a volunteer for the Senior USGA Amateur championship. Tom Watson won a Senior PGA major last week in Oregon, with his long-time caddy Bruce Edwards on the bag. Edwards has been diagnosed with ALS. The website for their fundraising effort to find a cure is here at Driving4Life.org.